Update of the Post-Splenectomy Vaccination Protocol and Educational Measures in the Prevention of Severe Sepsis

Authors

  • Andreia J. Santos Serviço de Cirurgia Geral da Unidade Local de Saúde de Viseu Dão-Lafões, Viseu, Portugal; CACB – Clinical Academic Centre of Beiras, Covilhã, Portugal https://orcid.org/0000-0002-3312-8882
  • Liliana Duarte Serviço de Cirurgia Geral da Unidade Local de Saúde de Viseu Dão-Lafões, Viseu, Portugal; CACB – Clinical Academic Centre of Beiras, Covilhã, Portugal; Faculty of Health Sciences – University of Beira Interior, Covilhã, Portugal https://orcid.org/0000-0001-8547-2725
  • Carolina Canhoto Serviço de Cirurgia Geral da Unidade Local de Saúde de Viseu Dão-Lafões, Viseu, Portugal; CACB – Clinical Academic Centre of Beiras, Covilhã, Portugal https://orcid.org/0000-0002-5152-9823
  • André Tojal Serviço de Cirurgia Geral da Unidade Local de Saúde de Viseu Dão-Lafões, Viseu, Portugal; CACB – Clinical Academic Centre of Beiras, Covilhã, Portugal https://orcid.org/0000-0002-2677-3736
  • Marta Ferreira Serviço de Cirurgia Geral da Unidade Local de Saúde de Viseu Dão-Lafões, Viseu, Portugal; CACB – Clinical Academic Centre of Beiras, Covilhã, Portugal https://orcid.org/0000-0001-7161-4286
  • Conceição Marques Serviço de Cirurgia Geral da Unidade Local de Saúde de Viseu Dão-Lafões, Viseu, Portugal; CACB – Clinical Academic Centre of Beiras, Covilhã, Portugal
  • Jorge Pereira Serviço de Cirurgia Geral da Unidade Local de Saúde de Viseu Dão-Lafões, Viseu, Portugal; CACB – Clinical Academic Centre of Beiras, Covilhã, Portugal https://orcid.org/0000-0002-3496-1710

DOI:

https://doi.org/10.34635/rpc.1142

Keywords:

Immunization, Secondary, Postoperative Care, Postoperative Complications, Sepsis/prevention & control, Splenectomy

Abstract

Anatomical or functional asplenia is associated with immunodeficiency and a significantly increased risk of life-threatening infections caused by encapsulated bacteria, such as Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis. These infections can rapidly progress to overwhelming post-splenectomy infection (OPSI), with high mortality. Prevention through vaccination, antibiotic prophylaxis, and patient education is essential to reduce morbidity and mortality in this population. We aimed to update the post-splenectomy vaccination protocol previously published in 2014, incorporating the most recent scientific evidence and national and international recommendations, and to propose an updated version of the “Post-Splenectomy Patient Record Booklet” to standardize clinical practice and strengthen coordination with Primary Health Care.

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Published

2025-12-22

Issue

Section

Original Papers

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