Primary Thyroid Lymphoma: Two Clinical Cases with Different Presentation

Authors

  • Daniela Gaspar General Surgery Department, Unidade Local de Saúde Viseu Dão Lafões, Viseu, Portugal https://orcid.org/0000-0003-3789-4653
  • João Vicente General Surgery Department, Unidade Local de Saúde Viseu Dão Lafões, Viseu, Portugal
  • Aline Gomes General Surgery Department, Unidade Local de Saúde Viseu Dão Lafões, Viseu, Portugal
  • Ana Oliveira General Surgery Department, Unidade Local de Saúde Viseu Dão Lafões, Viseu, Portugal
  • Jorge Pereira General Surgery Department, Unidade Local de Saúde Viseu Dão Lafões, Viseu, Portugal

DOI:

https://doi.org/10.34635/rpc.1091

Keywords:

Lymphoma, Lymphoma, B-Cell, Lymphoma, Large B-Cell, Diffuse, Thyroid Neoplasms/surgery

Abstract

Primary thyroid lymphoma (PTL) is a rare malignancy representing less than 5% of all thyroid cancers. It predominantly affects females and is strongly associated with Hashimoto thyroiditis, with an almost 60-fold increased risk in these patients.

In this report, the authors present two clinical cases of Primary Thyroid Lymphoma, each with distinct clinical presentations. They highlight the diagnostic challenges and the importance of early recognition and appropriate management.  

Downloads

Download data is not yet available.

References

Kakkar A, Purkait S, Agarwal S, Mallick S, Gogia A, Karak AK, et al. Primary thyroid lymphoma: A series from a tertiary care center in Northern India. J Cancer Res Ther. 2019;15:669–75. doi: 10.4103/jcrt.JCRT_135_17.

Pedersen RK, Pedersen NT. Primary non-Hodgkin’s lymphoma of the thyroid gland: a population-based study. Histopathology. 1996;28:25-32. doi: 10.1046/j.1365-2559.1996.268311.x.

Klubo-Gwiezdzinska J, Wartofsky L. Hashimoto thyroiditis: an evidence-based guide: etiology, diagnosis, and treatment. Pol Arch Intern Med. 2022;132:16222. doi: 10.20452/pamw.16222.

Khanal P, Lageju N, Adhikari B. Diffuse large B-cell lymphoma of thyroid: a case report and review of literature. Indian J Otolaryngol Head Neck Surg. 2022;74:2287-90. doi: 10.1007/s12070-020-02088-1.

Kesireddy M, Lasrado S. Thyroid Lymphoma. In: StatPearls. Treasure Island: StatPearls Publishing; 2025.

Downloads

Published

2025-03-31

Issue

Section

Clinical Case