PREOPERATIVE PHYSICAL ACTIVITY LEVELS AND POSTOPERATIVE BURDEN IN CANCER PATIENTS: A PROSPECTIVE OBSERVATIONAL STUDY

Rodrigo Cardoso; Mariana Guedes; Nicolle Pauli; Gabriela Ehrenbrink; Keily Poças; Carolina Castro; Carla Salomé Santos; Cristine Schmidt; Daniel Moreira-Gonçalves

doi:10.34635/rpc.932

Rodrigo Cardoso Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal
Mariana Guedes Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal
Nicolle Pauli Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal
Gabriela Ehrenbrink Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal
Keily Poças Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal
Carolina Castro Experimental Pathology and Therapeutics Group, Portuguese Oncology Institute of Porto FG, EPE (IPO-Porto), Porto, Portugal http://orcid.org/0000-0001-8156-4470
Carla Salomé Santos Experimental Pathology and Therapeutics Group, Portuguese Oncology Institute of Porto FG, EPE (IPO-Porto), Porto, Portugal
Cristine Schmidt Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal; Cardiovascular R& D Center (UnIC) and Department of Physiology and Cardiothoracic Surgery, Faculty of Medicine, University of Porto, Porto, Portugal http://orcid.org/0000-0002-8090-2068
Daniel Moreira-Gonçalves Research Center in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sport, University of Porto, Porto, Portugal; Experimental Pathology and Therapeutics Group, Portuguese Oncology Institute of Porto FG, EPE (IPO-Porto), Porto, Portugal http://orcid.org/0000-0002-7404-7405

Resumo

Introdução: Há um interesse crescente em entender o impacto dos níveis de atividade física (AF) pré-operatória na morbimortalidade pós-operatória. O presente trabalho teve como objetivo avaliar os níveis de AF em doentes com cancro da cabeça/pescoço ou estômago e comparar o desfecho pós-operatório entre aqueles que “aderem” ou “não aderem” às recomendações de AF.

Métodos: Foi realizado um estudo observacional, longitudinal e prospetivo em doentes recém-diagnosticados com cancro da cabeça/pescoço ou estômago, recrutados no IPO-Porto. Os níveis de AF foram avaliados por acelerometria. Os dados sobre o desfecho pós-operatório (complicações, tempo de internamento e mortalidade) foram consultados nos registos clínicos.

Resultados: Foram recrutados 81 doentes, a maioria homens (76,5%), com idade média de 61,8 ± 11,55 anos, peso de 69,08 ± 15,55 kg e IMC de 25,82 ± 5,29 kg / m2. Cinquenta e quatro doentes tinham diagnóstico de cancro do estômago (66,7%) e 27 tinham cancro da cabeça/pescoço (33,3%). Os doentes passaram 54% do tempo de uso em comportamento sedentário, 42% em AF leve e 4% em AF moderada a vigorosa (AFMV). A mediana semanal de AFMV foi de 132 (3-1860) min, e apenas 46,9% dos doentes cumpriram as recomendações mínimas de AFMV / semana. Não foram observadas diferenças entre os doentes cancro da cabeça/pescoço ou estômago. Em relação ao desfecho pós-operatório, 23,4% dos doentes apresentaram complicações minor e 12,5%, complicações major. O tempo de internamento hospitalar foi de 13,86 ± 15,58 dias e ocorreram 9,9% mortes no período pós-operatório. A mortalidade pós-operatória foi superior entre os doentes que ou “não aderem” as recomendações internacionais de AF (7 vs. 1 óbito).

Conclusão: Os nossos dados sugerem que níveis elevados de AF no pré-operatório reduzem o risco de mortalidade pós-operatória. A avaliação dos níveis de AF pré-operatória poderá auxiliar na identificação dos doentes com maior risco cirúrgico e orientá-los para intervenções de otimização pré-operatória, como a pré-habilitação.

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NÍVEIS DE ATIVIDADE FÍSICA PRÉ-OPERATÓRIA E PROGNÓSTICO PÓS-CIRÚRGICO EM DOENTES ONCOLÓGICOS: UM ESTUDO OBSERVACIONAL PROSPETIVO

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