Gangliocytic paraganglioma of ampulla of Vater: Clinical case

  • Isabel Mesquita Interna Complementar Cirurgia Geral 3º ano
  • José Maria de la Peña Assistente Hospitalar
  • Jaime Vilaça Assistente Hospitalar
  • José Davide Assistente Hospitalar Graduado
  • Jorge Daniel Assistente Hospitalar Graduado
  • Luís Graça Assistente Hospitalar Graduado
  • Manuel Teixeira Director de Serviço


First described in 1962, Gangliocytic Paraganglioma (GP) is a rare tumor that has been increasingly reported in the lite- rature since then.

It almost occurs in the second part of the duodenum, often at the Ampulla of Vater and the most common presenting sympton is, gastrointestinal bleeding.

Its characteristic histologic appearance consists of a mixture of three types in varying proportion: epithelioid, spindled and ganglion cells.

Almost reported cases of GP has followed a benign course however, regional lymph node metastasis has been reported.

Transduodenal local resection is a good treatment for benign ampullary tumors and it can be accomplished with little morbidity and a low recurrence rate.

Prolonged surveillance is indicated for local resections.
Key-words: Gangliocytic Paraganglioma, Ampulla of Vater, Transduodenal local resection 


Download data is not yet available.
How to Cite
MESQUITA, Isabel et al. Gangliocytic paraganglioma of ampulla of Vater: Clinical case. Revista Portuguesa de Cirurgia, [S.l.], n. 2, p. 37-42, sep. 2007. ISSN 2183-1165. Available at: <>. Date accessed: 25 apr. 2024.
Clinical Case