GIST and follicular lymphoma in a rare association – unusual intestinal occlusion case-report

  • José Pinto Hospital de Braga
  • Ana Ribeiro Hospital de Braga
  • Teresa Carneiro Hospital de Braga
  • Dina Luis Hospital de Braga
  • António Gomes Hospital de Braga


GISTs are stromal tumors considered to be sporadic. However, more and more studies describe association between these cancer and other tumors. The association of GIST to lymphomas is particularly rare because the molecular pathway in their development has nothing in common. The authors review the issue and report a case of GIST and follicular-lymphoma association based from a clinical history of a man, 79 years old, subjected to laparotomy in March 2013 because of an intra-abdominal mass of unknown etiology that was causing sub-occlusion, with ongoing worsening pain and abdominal discomfort. The histology of the resected tumor mass documented the presence of an association of a high-risk GIST with a follicular lymphoma. GISTs are rare and have sporadic associations to other cancers. This poorly understood connection can hide diagnostic surprises, you should never forget when we address this type of tumor. Therefore GIST’s patients are the clear example that all patients should be well studied preoperatively and followed cautiously postoperatively.


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Author Biographies

José Pinto, Hospital de Braga

Interno de Cirurgia Geral, Hospital de Braga

Ana Ribeiro, Hospital de Braga

Assistente de Cirurgia Geral

Teresa Carneiro, Hospital de Braga

Assistente de Cirurgia Geral

Dina Luis, Hospital de Braga

Assistente Graduada de Cirurgia Geral

António Gomes, Hospital de Braga

Chefe de Serviço de Cirurgia Geral


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3. Karanikas M, Machairiotis N, Zarogoulidis P, et al. Non-Hodgkin lymphoma and GIST: molecular pathways and clinical expressions. Onco Targets Ther. 2012; 5:433-8
4. Zinner MJ, Ashley SW, Maingot’s abdominal operations – 11th ed, pp 621-622
5. National Comprehensive Cancer Network, Soft Tissue Sarcoma – v2.2106
How to Cite
PINTO, José et al. GIST and follicular lymphoma in a rare association – unusual intestinal occlusion case-report. Revista Portuguesa de Cirurgia, [S.l.], n. 44, p. 7 - 12, sep. 2018. ISSN 2183-1165. Available at: <>. Date accessed: 09 dec. 2023.
Clinical Case