TOTALLY IMPLANTABLE VENOUS ACCESS DEVICES IN ONCOLOGY: RETROSPECTIVE ANALYSIS OF 652 PATIENTS

  • Filipa Ferreira da Silva Department of Oncology, Hospital da Luz, Lisboa, Portugal
  • Vanessa Novais de Carvalho Department of Internal Medicine, Hospital da Luz, Lisboa, Portugal
  • Pedro Moraes Sarmento Department of Internal Medicine, Hospital da Luz, Lisboa, Portugal
  • Mónica Nave Department of Oncology, Hospital da Luz, Lisboa, Portugal
  • José Luís Passos-Coelho Department of Oncology, Hospital da Luz, Lisboa, Portugal

Abstract

Introduction: Adequate venous access is essential for the treatment and management of cancer patients. Insertion of totally implantable venous access devices (TIVADs) provide a safe method for chemotherapy (ChT) administration, but it’s not free of complications. We aim to analyze our institution clinical practice experience regarding TIVADs.


Materials and Methods: Electronic medical records (EMR) review of all cancer patients that required placement of a TIVAD at Hospital da Luz between January 1st 2008 and December 31st 2014.


Results: Clinical data from 652 cancer patients was retrospectively reviewed. The overall incidence of complications was 14.1% (91), with only 6 (0.9%) being early complications (before the first clinical TIVAD utilization). The most common complications were thrombosis (30, 4.5%) and infections (TIVAD related and cutaneous, 24, 3.5%), followed by exteriorization (13, 1.9%) and catheter dysfunction (11,1.6%). 155 TIVADs were removed, the majority (95, 61.3%) because of end of treatment and the remainder (60; 38.7%) due to catheter complications.


Discussion: Global complication rate was as expected, however we observed a low rate of early complications, and we didn’t observe any potentially fatal complication related to the procedure. Unlike expected, thrombotic complications were the most frequent, followed by infectious complications.


Conclusions: TIVADs insertion is a safe procedure in cancer patients with an apparent low rate of complications with no fatal events identified in this study.

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References

1. Keum DY, Kim JB, Chae MC: Safety of a Totally Implantable Central Venous Port System with Percutaneous Subclavian Vein Access. Korean J Thorac Cardiovasc Surg 2013; 46:202-207.

2. Granic M, Zdravkovic D, Krstajic S, et al.: Totally implantable central venous catheters of the port-a-cath type: complications due to its use in the treatment of cancer patients. JBUON 2014; 19: 842-846.

3. Granziera E, Scarpa M, Ciccarese A, et al.: Totally implantable venous access devices: retrospective analysis of different insertion techniques and predictors of complications in 796 devices implanted in a single institution. BMC Surgery 2014;14:27.

4. An H, Ryu CG, Jung EJ, et al.: Insertion of Totally Implantable Central Venous Access Devices by Surgeons. Ann Coloproctol 2015; 31:63-67.

5. Niederhuber JE, Ensminger W, Gyves JW, et al.: Totally implanted venous and arterial access system to replace external catheters in cancer treatment. Surgery 1982; 92:706–712.

6. Schiffer CA, Mangu PB, Wade JC, et al.: Central Venous Catheter Care for the Patient With Cancer: American Society of Clinical Oncology Clinical Practice Guideline. J Clin Oncol 2013; 31:1357-1370

7. Gurkan S, Seber S, Gur O, et al.: Retrospective evaluation of totally implantable venous access port devices: Early and late complications. JBUON 2015; 20: 338-345.

8. Barbetakis N, Asteriou C, Kleontas A, et al.: Totally Implantable Central Venous Access Ports. Analysis of 700 Cases. Journal of Surgical Oncology 2011; 104:654–656.

9. Delluc A, Le Gal G, Scarvelis D, et al.: Outcome of central venous catheter associated upper extremity deep vein thrombosis in cancer patients. Thrombosis Research 2015; 135 298–302

10. National Comprehensive Cancer Network. Cancer-Associated Venous Thromboembolic Disease. Version 1.2016. https://www.nccn.org/professionals/physician_gls/pdf/vte.pdf. Accessed December 2017.

11. Oliveira E, Reis MA, Avelar TM, et al.: Totally implantable central venous catheters for chemotherapy: experience with 793 patients. Rev. Col. Bras. Cir. 2013; 40: 186-190.
Published
2020-07-02
How to Cite
FERREIRA DA SILVA, Filipa et al. TOTALLY IMPLANTABLE VENOUS ACCESS DEVICES IN ONCOLOGY: RETROSPECTIVE ANALYSIS OF 652 PATIENTS. Revista Portuguesa de Cirurgia, [S.l.], n. 47, p. 41-47, july 2020. ISSN 2183-1165. Available at: <https://revista.spcir.com/index.php/spcir/article/view/726>. Date accessed: 16 apr. 2024. doi: https://doi.org/10.34635/rpc.726.
Section
Original Papers