Ten Key Questions on the 2023 Bethesda “AUS” Category: Practical Guidance for Surgeons, Endocrinologists, and Pathologists
DOI:
https://doi.org/10.34635/rpc.1129Keywords:
Biopsy, Fine-Needle, Endocrine Surgical Procedures, Thyroid Neoplasms/pathology, Thyroid Neoplasms/surgery, Thyroid Nodule/pathologyAbstract
The 2023 Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) redefines Atypia of Undetermined Significance (AUS) by introducing subclassification into AUS with nuclear atypia and AUS-other. This change reflects growing evidence that the risk of malignancy is subtype-dependent. For endocrine surgeons, this means that cytology can no longer be interpreted in isolation: AUS subtypes must be integrated with ultrasound patterns and, when appropriate, molecular data to guide individualized management.
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